Oxidative Stress

Oxidative Stress arises from an imbalance between accumulating Free Radicals and the body's Antioxidant Defense System, leading to cellular damage, aging, and diseases. U.C. Berkeley Prof. L. Packer identified five key "Network Antioxidants": Glutathione, Alpha-Lipoic Acid (ALA), CoEnzyme Q10, Vitamins C & E. These Essential Nutrients, except for Vitamins C and E, naturally decline with age. Boosting Glutathione is essential, and Alpha-Lipoic Acid (ALA) can enhance the Antioxidant Network in both water and fat environments. GeranylGeraniol (GG) supports CoEnzyme Q10 production for energy and muscle health. Combining Delta-Tocotrienols and GG is recommended. Delta-Tocotrienols, especially the Delta- and Gamma-forms, are potent antioxidants protecting cellular membranes effectively.

Note: Antioxidant protection is vital for all 37 trillion cells in the human body. Vitamin E, particularly Delta-Tocotrienol, provides over 90% of this protection, with Delta-Tocotrienols being the most efficient. They act as the ultimate "Bodyguards" for cellular membranes, controlling the passage of life's molecules. Delta-Tocotrienols are champions of protection and prevention.

References

• PLOS ONE (2021) - Effects of tocotrienols supplementation on markers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials

• Nutrients (2021) - Dietary Annatto-Extracted Tocotrienol Reduces Inflammation and Oxidative Stress, and Improves Macronutrient Metabolism in Obese Mice: A Metabolic Profiling Study

• Journal of Functional Foods (2020) - Regulation of inflammatory response and oxidative stress by tocotrienol in a rat model of non-alcoholic fatty liver disease

• The Journal of Nutritional Biochemistry (2018) - Tocotrienol-rich fraction supplementation reduces hyperglycemia-induced skeletal muscle damage through regulation of insulin signaling and oxidative stress in type 2 diabetic mice

• Osteoporosis International (2018) - Tocotrienol supplementation suppressed bone resorption and oxidative stress in postmenopausal osteopenic women: a 12-week randomized double-blinded placebo-controlled trial

• Experimental and Therapeutic Medicine (2017) - Tocotrienol alleviates inflammation and oxidative stress in a rat model of spinal cord injury via suppression of transforming growth factor-β

• International Journal of Molecular Sciences (2016) - Tocotrienol Affects Oxidative Stress, Cholesterol Homeostasis and the Amyloidogenic Pathway in Neuroblastoma Cells: Consequences for Alzheimer’s Disease

• Clinical & Experimental Cardiology (2015) - Impact of δ-Tocotrienol on Inflammatory Biomarkers and Oxidative Stress in Hypercholesterolemic Subjects